TB-500 is a synthetic peptide corresponding to the amino acid sequence 17–23 of the naturally occurring protein Thymosin Beta-4 (Tβ4). Unlike BPC-157, which acts locally through growth factor upregulation, TB-500's primary mechanism involves actin sequestration — it binds G-actin monomers and promotes cell migration and proliferation in injured tissue.
Thymosin Beta-4 is endogenously produced by platelets and is released at wound sites, suggesting a natural role in the healing cascade. The TB-500 fragment retains the core actin-binding domain and has demonstrated systemic distribution in research models — an important distinction from peptides with more localized activity.
TB-500 is frequently studied alongside BPC-157 (the "Wolverine Stack") because their complementary mechanisms — systemic cell migration (TB-500) and local growth factor upregulation (BPC-157) — may produce additive effects in tissue repair research models. Both compounds have no FDA approval and are for laboratory research only.
Third-party tested · Lot-specific COA · US domestic shipping 24–48h
Buy TB-500 Now →| Purity | ≥99% (HPLC verified, third-party) |
| Molecular Weight | 6,981.9 Da |
| Appearance | White to off-white lyophilized powder |
| Storage | –20°C long-term; 4°C up to 14 days after reconstitution |
| Lot Number | OL-2026-006 |
| Format | Lyophilized powder, sealed vial |
| Certificate of Analysis | Lot-specific COA included with every order |
| Intended Use | In vitro laboratory research only |
| Source | Synthetic analog of Thymosin Beta-4 fragment (AA 17–23) |
Research Use Disclaimer: TB-500 is sold strictly for in vitro laboratory research purposes only. Not for human consumption, veterinary use, or clinical application. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.